popellab.johnshopkins.eduPopel Systems Biology Laboratory The Systems Biology Laboratory at Johns Hopkins University
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Title:Popel Systems Biology Laboratory The Systems Biology Laboratory at Johns Hopkins University
Description:Popel Systems Biology Laboratory Home News Research People Software Publications Positions Gallery Visualizing the Heterogeneity of Tumor Vasculature In silico simulation for cancer immunotherapy Reve
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Popel Systems Biology Laboratory Home News Research People Software Publications Positions Gallery Visualizing the Heterogeneity of Tumor Vasculature In silico simulation for cancer immunotherapy Reversing the loss of sight. Protein-protein interactions in peripheral arterial disease Breast cancer metastasis in the lung: blood and lymphatic microvessels Systems pharmacology of VEGF in cancer Agent-based modeling of tumor growth and metastasis Transcriptional and post-transcriptional regulation of thrombospondin-1 expression Therapeutic peptide activates receptor Tie-2 and decreases endothelial cell permeability. Approved HIV and rheumatoid arthritis drugs for treating breast cancer Systems pharmacology model of cancer immune checkpoint inhibition Research Interests Our laboratory focuses on applying combinations of computational modeling, bioinformatics, and in vitro and in vivo experimentation (systems biology approaches) to solve problems related to cancer,cardiovascular and ocular diseases. System biology and multiscale modeling have emerged as powerful methodologies to integrate the data from a variety of sources and at different levels of biological organization spanning multiple spatial and temporal scales. READ MORE Popel Lab Department of Biomedical Engineering School of Medicine Johns Hopkins University 720 Rutland Avenue 611 Traylor Research Bldg. Baltimore, MD 21205 Contact p. 410-955-6419 f. 410-614-8796 apopel@jhu.edu Home News Research People Software Publications Positions Gallery © 2020 Popel Systems Biology Laboratory. --...